GTX131332
MACC1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX131332
- Zusätzliche Namen:
- MET transcriptional regulator MACC1 , 7A5 , SH3BP4L
- Anwendung:
- WB
- Konzentration:
- 1.14 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human MACC1. The exact sequence is proprietary.
- Uniprot:
- Q6ZN28
- Synonyme:
- 7A5;MACC1, MET transcriptional regulator;metastasis associated in colon cancer 1;metastasis-associated in colon cancer protein 1;putative binding protein 7a5;SH3 domain-containing protein 7a5;SH3BP4L
- Weitere Details:
- MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]
- Versandbedingungen:
- Blue Ice