GTX131024
PSTPIP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX131024
- Zusätzliche Namen:
- proline-serine-threonine phosphatase interacting protein 1 , CD2BP1 , CD2BP1L , CD2BP1S , H-PIP , PAPAS , PSTPIP
- Anwendung:
- WB
- Konzentration:
- 0.63 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human PSTPIP1. The exact sequence is proprietary.
- Uniprot:
- O43586
- Synonyme:
- CD2 antigen-binding protein 1;CD2 cytoplasmic tail-binding protein;CD2-binding protein 1;CD2BP1;CD2BP1L;CD2BP1S;H-PIP;PAPAS;PEST phosphatase-interacting protein 1;proline-serine-threonine phosphatase-interacting protein 1;PSTPIP;truncated proline-serine-threonine phosphatase interacting protein 1
- Weitere Details:
- The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice