GTX130978
Sclerostin antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX130978
- Zusätzliche Namen:
- sclerostin , CDD , DAND6 , SOST1 , VBCH
- Anwendung:
- WB
- Konzentration:
- 2.73 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Sclerostin. The exact sequence is proprietary.
- Uniprot:
- Q9BQB4
- Synonyme:
- CDD;DAND6;sclerostin;SOST1;VBCH
- Weitere Details:
- Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice