GTX130803
DIAPH3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX130803
- Zusätzliche Namen:
- diaphanous related formin 3 , AN , AUNA1 , DIA2 , DRF3 , NSDAN , diap3 , mDia2
- Anwendung:
- WB, IHC-P
- Konzentration:
- 2.13 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Rat
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.
- Uniprot:
- Q9NSV4
- Synonyme:
- AN;AUNA1;DIA2;diap3;diaphanous homolog 3;Diaphanous-related formin-3;DRF3;mDia2;NSDAN;protein diaphanous homolog 3
- Weitere Details:
- Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.
- Versandbedingungen:
- Blue Ice