GTX130503
Kiss1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX130503
- Zusätzliche Namen:
- KiSS-1 metastasis suppressor , HH13 , KiSS-1
- Anwendung:
- WB
- Konzentration:
- 1.07 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Kiss1. The exact sequence is proprietary.
- Uniprot:
- Q15726
- Synonyme:
- HH13;KiSS-1;kisspeptin-1;malignant melanoma metastasis-suppressor;metastasis-suppressor KiSS-1;metastin;prepro-kisspeptin
- Weitere Details:
- This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice