GTX130500
EDEM1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX130500
- Zusätzliche Namen:
- ER degradation enhancing alpha-mannosidase like protein 1 , EDEM
- Anwendung:
- WB
- Konzentration:
- 1.21 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human EDEM1. The exact sequence is proprietary.
- Uniprot:
- Q92611
- Synonyme:
- EDEM;ER degradation enhancer, mannosidase alpha-like 1;ER degradation-enhancing alpha-mannosidase-like 1;ER degradation-enhancing alpha-mannosidase-like protein 1
- Weitere Details:
- Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.
- Versandbedingungen:
- Blue Ice