GTX130167
HERC5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX130167
- Zusätzliche Namen:
- HECT and RLD domain containing E3 ubiquitin protein ligase 5 , CEB1 , CEBP1
- Anwendung:
- WB
- Konzentration:
- 3.96 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human HERC5. The exact sequence is proprietary.
- Uniprot:
- Q9UII4
- Synonyme:
- CEB1;CEBP1;cyclin-E-binding protein 1;E3 ISG15--protein ligase HERC5;HECT domain and RCC1-like domain-containing protein 5;hect domain and RLD 5;probable E3 ubiquitin-protein ligase HERC5
- Weitere Details:
- This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice