GTX129783
RBM5 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX129783
- Zusätzliche Namen:
- RNA binding motif protein 5 , G15 , H37 , LUCA-15 , LUCA15 , RMB5
- Anwendung:
- WB, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human RBM5. The exact sequence is proprietary.
- Uniprot:
- P52756
- Synonyme:
- G15;H37;LUCA-15;LUCA15;Protein G15;putative tumor suppressor LUCA15;renal carcinoma antigen NY-REN-9;RMB5;RNA-binding motif protein 5;RNA-binding protein 5
- Weitere Details:
- Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
- Versandbedingungen:
- Blue Ice