GTX129438
Ikaros antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX129438
- Zusätzliche Namen:
- IKAROS family zinc finger 1 , CVID13 , Hs.54452 , IK1 , IKAROS , LYF1 , LyF-1 , PPP1R92 , PRO0758 , ZNFN1A1
- Anwendung:
- ChIP, WB, IP
- Konzentration:
- 0.38 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human Ikaros. The exact sequence is proprietary.
- Uniprot:
- Q13422
- Synonyme:
- CLL-associated antigen KW-6;CVID13;DNA-binding protein Ikaros;Hs.54452;IK1;IKAROS;ikaros family zinc finger protein 1;LyF-1;LYF1;lymphoid transcription factor LyF-1;PPP1R92;PRO0758;protein phosphatase 1, regulatory subunit 92;zinc finger protein, subfamily 1A, 1 (Ikaros);ZNFN1A1
- Weitere Details:
- Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).
- Versandbedingungen:
- Blue Ice