GTX129141
PITX2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX129141
- Zusätzliche Namen:
- paired like homeodomain 2 , ARP1 , ASGD4 , Brx1 , IDG2 , IGDS , IGDS2 , IHG2 , IRID2 , Otlx2 , PTX2 , RGS , RIEG , RIEG1 , RS
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human PITX2. The exact sequence is proprietary.
- Uniprot:
- Q99697
- Synonyme:
- all1-responsive gene 1;ALL1-responsive protein ARP1;ARP1;ASGD4;Brx1;homeobox protein PITX2;IDG2;IGDS;IGDS2;IHG2;IRID2;Otlx2;paired-like homeodomain transcription factor 2;pituitary homeobox 2;PTX2;RGS;RIEG;RIEG bicoid-related homeobox transcription factor;rieg bicoid-related homeobox transcription factor 1;RIEG1;RS;solurshin
- Weitere Details:
- This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice