GTX129028
PHF2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX129028
- Zusätzliche Namen:
- PHD finger protein 2 , CENP-35 , GRC5 , JHDM1E , KDM7C
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human PHF2. The exact sequence is proprietary.
- Uniprot:
- O75151
- Synonyme:
- CENP-35;centromere protein 35;GRC5;JHDM1E;jumonji C domain-containing histone demethylase 1E;KDM7C;lysine-specific demethylase PHF2;PHD finger protein 2
- Weitere Details:
- Probable regulator of histone methyltransferase complexes. Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA. Was reported to have histone demethylase activity by itself and specifically demethylate monomethylated 'Lys-9' of histone H3 (H3K9me1), an epigenetic repressive mark. However, this activity is unclear in vivo and requires additional evidence.
- Versandbedingungen:
- Blue Ice