GTX128415
AKT antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX128415
- Zusätzliche Namen:
- AKT antibody , MGC99656 antibody , PKB antibody , PKB-ALPHA antibody , PRKBA antibody , RAC antibody , RAC-ALPHA antibody , AKT1 antibody , protein kinase B alpha antibody , rac protein kinase alpha antibody , RAC-alpha serine/threonine-protein kinase antibody , proto-oncogene c-Akt antibody , RAC-PK-alpha antibody , PKB alpha antibody , v-akt murine thymoma viral oncogene homolog 1 antibody , PKBB antibody , PKBBETA antibody , PRKBB antibody , RAC-BETA antibody , AKT2 antibody , protein
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Insect/Arthropod
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Akt1/2/3. The exact sequence is proprietary.
- Synonyme:
- AKT;AKT1m;PKB;PKB alpha;PKB-ALPHA;PRKBA;protein kinase B alpha;proto-oncogene c-Akt;RAC;rac protein kinase alpha;RAC-ALPHA;RAC-alpha serine/threonine-protein kinase;RAC-PK-alpha;serine-threonine protein kinase;v-akt murine thymoma viral oncogene homolog 1;v-akt murine thymoma viral oncogene-like protein 1
- Weitere Details:
- The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice