GTX128254
MYSM1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX128254
- Zusätzliche Namen:
- Myb like, SWIRM and MPN domains 1 , 2A-DUB , 2ADUB , BMFS4
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human MYSM1. The exact sequence is proprietary.
- Uniprot:
- Q5VVJ2
- Synonyme:
- 2A-DUB;2ADUB;BMFS4;deubiquitinase MYSM1;histone H2A deubiquitinase MYSM1;myb-like, SWIRM and MPN domain-containing protein 1
- Weitere Details:
- Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
- Versandbedingungen:
- Blue Ice