TPO antibody [MoAb47]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX12500
Zusätzliche Namen:: thyroid peroxidase , MSA , TDH2A , TPX
Anwendung:: IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Unpurified
Lagerbedingungen:: 2-8[o]C
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: Human thyroid peroxidase (hTPO) purified from thyroid microsomes by immunoaffinity chromatography.
Klon:: MoAb47
Uniprot:: P07202
Synonyme:: MSA;TDH2A;thyroid microsomal antigen;thyroid peroxidase;thyroperoxidase;TPX
Weitere Details:: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]