![APP antibody [3E9]](https://www.genetex.com/upload/website/prouct_img/normal/GTX12338/Amyloid-Precursor-Protein-antibody-3E9_WB_GTX12338-1_w_23060522_626.webp)
GTX12338
APP antibody [3E9]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX12338
- Zusätzliche Namen:
- amyloid beta precursor protein , AAA , ABETA , ABPP , AD1 , APPI , CTFgamma , CVAP , PN-II , PN2 , preA4
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 1% Sucrose, no preservatives.
- Immunogen:
- Synthetic peptide: LEVPTDGNAGLLAEPQIAMFC , corresponding to amino acids 18-38 of Human Amyloid Precursor Protein.
- Klon:
- 3E9
- Uniprot:
- P05067
- Synonyme:
- AAA;ABETA;ABPP;AD1;alpha-sAPP;alzheimer disease amyloid protein;amyloid beta (A4) precursor protein;amyloid beta A4 protein;amyloid precursor protein;amyloid-beta precursor protein;APPI;beta-amyloid peptide;beta-amyloid peptide(1-40);beta-amyloid peptide(1-42);beta-amyloid precursor protein;cerebral vascular amyloid peptide;CTFgamma;CVAP;peptidase nexin-II;PN-II;PN2;preA4;protease nexin-II;testicular tissue protein Li 2
- Weitere Details:
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
- Versandbedingungen:
- Blue Ice