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  2. Polyclonal

GTX12316

APLP1 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX12316
Anwendung:
WB, IHC-P
Konzentration:
500 ug/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA, 0.025% Thimerosal, 0.025% Sodium azide.
Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human APLP1(101-120aa ELQIARVEQATQAIPMERWC), different from the related mouse and rat sequences by two amino acids.
Uniprot:
P51693
Synonyme:
amyloid beta (A4) precursor-like protein 1;amyloid precursor-like protein 1;amyloid-like protein 1;APLP
Weitere Details:
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice