GTX12314
PMP70 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX12314
- Anwendung:
- WB, IHC-P
- Konzentration:
- 500 ug/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA, 0.025% Thimerosal, 0.025% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence at the C-terminus of human PMP70(646-659aa EFKQITEDTVEFGS), different from the related mouse and rat sequences by one amino acid.
- Uniprot:
- P28288
- Synonyme:
- 70 kDa peroxisomal membrane protein;ABC43;ATP-binding cassette sub-family D member 3;ATP-binding cassette, sub-family D (ALD), member 3;CBAS5;dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1));peroxisomal membrane protein 1 (70kD, Zellweger syndrome);peroxisomal membrane protein 70 kDa;Peroxisomal membrane protein-1 (70kD);PMP70;PXMP1;ZWS2
- Weitere Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice