GTX122802
CYFIP1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX122802
- Zusätzliche Namen:
- cytoplasmic FMR1 interacting protein 1 , P140SRA-1 , SHYC , SRA-1 , SRA1
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human CYFIP1. The exact sequence is proprietary.
- Uniprot:
- Q7L576
- Synonyme:
- cytoplasmic FMR1-interacting protein 1;cytoplasmic FMRP interacting protein 1;P140SRA-1;selective hybridizing clone;SHYC;specifically Rac1-associated protein 1;SRA-1;SRA1
- Weitere Details:
- Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.
- Versandbedingungen:
- Blue Ice