ASGPR1 antibody [N1C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX122674
Zusätzliche Namen:: asialoglycoprotein receptor 1 , ASGPR , ASGPR1 , CLEC4H1 , HL-1
Anwendung:: WB, IF, ICC
Konzentration:: 0.3 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
Immunogen:: Recombinant protein encompassing a sequence within the Extracellular domain of human ASGPR1. The exact sequence is proprietary.
Klon:: N1C3
Uniprot:: P07306
Synonyme:: ASGPR;ASGPR1;asialoglycoprotein receptor 1;C-type lectin domain family 4 member H1;CLEC4H1;hepatic lectin H1;HL-1
Weitere Details:: Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. [provided by RefSeq]