GTX122197
KLB antibody [N1N3]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX122197
- Zusätzliche Namen:
- klotho beta , BKL
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the Extracellular domain of human KLB. The exact sequence is proprietary.
- Klon:
- N1N3
- Uniprot:
- Q86Z14
- Synonyme:
- b-Klotho;beta-klotho;betaKlotho;BKL;klotho beta like;klotho beta-like protein
- Weitere Details:
- Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
- Versandbedingungen:
- Blue Ice