GTX12170
HDAC4 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX12170
- Zusätzliche Namen:
- histone deacetylase 4 , AHO3 , BDMR , HA6116 , HD4 , HDAC-4 , HDAC-A , HDACA
- Anwendung:
- WB, IF, ICC, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 15mM Sodium azide.
- Immunogen:
- synthetic peptide corresponding to amino acid residues 14-28 of human HDAC4 with C-terminal added lysine conjugated to KLH.
- Uniprot:
- P56524
- Synonyme:
- AHO3;BDMR;HA6116;HD4;HDAC-4;HDAC-A;HDACA;histone deacetylase 4;histone deacetylase A
- Weitere Details:
- Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional machinery for expression. Histone deacetylases (HDACs) are chromatin remodeling factors that deacetylate histone proteins and thus, may act as transcriptional repressors. HDACs are classified by their sequence homology to the yeast HDACs and there are currently 2 classes. Class I proteins are related to Rpd3 and members of class II resemble Hda1p.
- Versandbedingungen:
- Blue Ice