GTX121127
UBXN1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX121127
- Zusätzliche Namen:
- UBX domain protein 1 , 2B28 , SAKS1 , UBXD10
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 0.78 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human UBXN1. The exact sequence is proprietary.
- Uniprot:
- Q04323
- Synonyme:
- 2B28;SAKS1;SAPK substrate protein 1;UBA/UBX 33.3 kDa protein;UBX domain-containing protein 1;UBXD10
- Weitere Details:
- Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.
- Versandbedingungen:
- Blue Ice