GTX120298
WDYHV1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX120298
- Zusätzliche Namen:
- WDYHV motif containing 1 , C8orf32
- Anwendung:
- IHC-P, IF, ICC
- Konzentration:
- 0.58 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human WDYHV1. The exact sequence is proprietary.
- Uniprot:
- Q96HA8
- Synonyme:
- C8orf32;N-terminal Gln amidase;nt(Q)-amidase;protein N-terminal glutamine amidohydrolase;protein NH2-terminal glutamine deamidase;WDYHV motif containing 1;WDYHV motif-containing protein 1;WDYHV1
- Weitere Details:
- Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
- Versandbedingungen:
- Blue Ice