GTX12019
NRG2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX12019
- Anwendung:
- WB
- Konzentration:
- 500 ug/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA, 0.025% Thimerosal, 0.025% Sodium azide.
- Immunogen:
- A synthetic peptide corresponding to a sequence in the middle region of human NRG2(289-306aa NGRKNSRLQFNKVKVEDA), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
- Uniprot:
- O14511
- Synonyme:
- divergent of neuregulin-1;DON1;HRG2;neural- and thymus-derived activator for ErbB kinases;NTAK;pro-neuregulin-2, membrane-bound isoform;pro-NRG2
- Weitere Details:
- This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010]
- Versandbedingungen:
- Blue Ice