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  2. Polyclonal

GTX119732

Rad50 antibody [C1C2], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX119732
Zusätzliche Namen:
RAD50 double strand break repair protein , NBSLD , RAD502 , hRad50
Anwendung:
WB, IHC-P, IP
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Rad50. The exact sequence is proprietary.
Klon:
C1C2
Uniprot:
Q92878
Synonyme:
DNA repair protein RAD50;hRad50;NBSLD;RAD50 homolog, double strand break repair protein;RAD502
Weitere Details:
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]
Versandbedingungen:
Blue Ice