NTAN1 antibody [N1C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX119378
Zusätzliche Namen:: N-terminal asparagine amidase , PNAA , PNAD
Anwendung:: WB, IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human NTAN1. The exact sequence is proprietary.
Klon:: N1C3
Uniprot:: Q96AB6
Synonyme:: PNAA;PNAD;protein N-terminal Asn amidase;protein N-terminal asparagine amidase;protein N-terminal asparagine amidohydrolase;Protein NH2-terminal asparagine amidohydrolase;protein NH2-terminal asparagine deamidase;protein NTN-amidase
Weitere Details:: Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position.

Versandbedingungen:: Blue Ice