DAP5 antibody [39C534.1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX11929
Zusätzliche Namen:: eukaryotic translation initiation factor 4 gamma 2 , AAG1 , DAP5 , NAT1 , P97
Anwendung:: Flow Cytometry, WB
Konzentration:: 0.5 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Hamster, Human, Mouse
Buffer:: PBS, 0.2% Gelatin, 0.05% Sodium azide.
Immunogen:: The antibody was raised against two synthetic peptides corresponding to amino acids 796-812 of human DAP-5 protein.
Klon:: 39C534.1
Uniprot:: P78344
Synonyme:: AAG1;aging-associated protein 1;DAP-5;DAP5;death-associated protein 5;eIF-4-gamma 2;eIF-4G 2;eIF4G 2;eukaryotic translation initiation factor 4 gamma 2;eukaryotic translation initiation factor 4G-like 1;NAT1;P97
Weitere Details:: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]

Versandbedingungen:: Blue Ice