GTX118817
IVNS1ABP antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX118817
- Zusätzliche Namen:
- influenza virus NS1A binding protein , ARA3 , FLARA3 , HSPC068 , KLHL39 , ND1 , NS-1 , NS1-BP , NS1BP
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.57 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the C-terminus region of human IVNS1ABP. The exact sequence is proprietary.
- Uniprot:
- Q9Y6Y0
- Synonyme:
- ARA3;aryl hydrocarbon receptor-associated 3;aryl hydrocarbon receptor-associated protein 3;FLARA3;HSPC068;IMD70;influenza virus NS1A-binding protein;kelch-like family member 39;kelch-like protein 39;KLHL39;NCX downstream gene 1;ND1;NS-1;NS1-binding protein;NS1-BP;NS1BP
- Weitere Details:
- Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
- Versandbedingungen:
- Blue Ice