GTX118735
NEK2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX118735
- Zusätzliche Namen:
- NIMA related kinase 2 , HsPK21 , NEK2A , NLK1 , PPP1R111 , RP67
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1.47 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 20% Glycerol, 0.025% ProClin 300.
- Immunogen:
- Recombinant protein corresponding to human NEK2.
- Uniprot:
- P51955
- Synonyme:
- HSPK 21;HsPK21;NEK2A;Never in mitosis A-related kinase 2;NIMA (never in mitosis gene a)-related kinase 2;nimA-like protein kinase 1;nimA-related protein kinase 2;NLK1;PPP1R111;protein phosphatase 1, regulatory subunit 111;RP67;serine/threonine-protein kinase Nek2
- Weitere Details:
- Protein kinase that is involved in mitotic regulation. Integral component of the mitotic spindle-assembly checkpoint which is necessary for proper chromosome segregation during metaphase-anaphase transition. Required for association of MAD2L1 to kinetochore. Phosphorylates SGOL1. May have a role at the G2-M transition. May also play a role in meiosis. Isoform 1 but not isoform 2 appears to play a role in centrosome splitting. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not.
- Versandbedingungen:
- Blue Ice