UBA3 antibody [N1N3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX118601
Zusätzliche Namen:: ubiquitin like modifier activating enzyme 3 , NAE2 , UBE1C , hUBA3
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the center region of human UBA3. The exact sequence is proprietary.
Klon:: N1N3
Uniprot:: Q8TBC4
Synonyme:: hUBA3;NAE2;NEDD8-activating enzyme E1 catalytic subunit;NEDD8-activating enzyme E1 subunit 2;NEDD8-activating enzyme E1C;Nedd8-activating enzyme hUba3;UBA3, ubiquitin-activating enzyme E1 homolog;UBE1C;ubiquitin-activating enzyme 3;Ubiquitin-activating enzyme E1C;ubiquitin-activating enzyme E1C (homologous to yeast UBA3);ubiquitin-activating enzyme E1C (UBA3 homolog, yeast);Ubiquitin-like modifier-activating enzyme 3
Weitere Details:: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]

Versandbedingungen:: Blue Ice