GTX11796
TIMP2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX11796
- Zusätzliche Namen:
- TIMP metallopeptidase inhibitor 2 , CSC-21K , DDC8
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 15mM Sodium azide.
- Immunogen:
- synthetic peptide corresponding to the first loop of human tissue inhibitor of metalloproteinase-2
- Uniprot:
- P16035
- Synonyme:
- CSC-21K;DDC8;metalloproteinase inhibitor 2;testicular secretory protein Li 57;tissue inhibitor of metalloproteinases 2
- Weitere Details:
- Matrix metalloproteinases (MMPs) are a family of enzymes that are responsible for the degradation of extracellular matrix components such as collagen, laminin and proteoglycans. These enzymes are involved in normal physiological processes such as embryogenesis and tissue remodeling and may play an important role in arthritis, periodontitis, and metastasis.The activation and activity of MMPs are regulated by a family of endogenous inhibitors, tissue inhibitors of metalloproteinase (TIMP). TIMP2 (also called CSC-21K) is a 21 kDa glycoprotein that is expressed by a variety of cell types. It forms a non-covalent, stoichiometric complex with both latent and active MMPs. TIMP2 shows a preference for MMP-2. TIMPs are capable of altering the metastatic potential of cancer cells and have been shown to inhibit invasion and metastasis in animal models.
- Versandbedingungen:
- Blue Ice