![SENP8 antibody [N1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX117839/GTX117839_40289_IHC_w_23060519_893.webp)
![SENP8 antibody [N1C3]](https://www.genetex.com/upload/website/prouct_img/normal/GTX117839/GTX117839_WB_w_23060519_837.webp)
GTX117839
SENP8 antibody [N1C3]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX117839
- Zusätzliche Namen:
- SUMO peptidase family member, NEDD8 specific , DEN1 , NEDP1 , PRSC2
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human SENP8. The exact sequence is proprietary.
- Klon:
- N1C3
- Uniprot:
- Q96LD8
- Synonyme:
- DEN1;deneddylase 1;Deneddylase-1;NEDD8 specific-protease cysteine 2;NEDD8-specific protease 1;NEDP1;protease, cysteine 2;PRSC2;sentrin-specific protease 8;Sentrin/SUMO-specific protease SENP8;SUMO sentrin specific protease family member 8;SUMO/sentrin peptidase family member, NEDD8 specific;SUMO/sentrin specific peptidase family member 8
- Weitere Details:
- NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM]
- Versandbedingungen:
- Blue Ice