GTX117475
MBTPS1 antibody [C1C3]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX117475
- Zusätzliche Namen:
- membrane bound transcription factor peptidase, site 1 , PCSK8 , S1P , SKI-1
- Anwendung:
- WB
- Konzentration:
- 0.89 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human MBTPS1. The exact sequence is proprietary.
- Klon:
- C1C3
- Uniprot:
- Q14703
- Synonyme:
- endopeptidase S1P;membrane-bound transcription factor site-1 protease;PCSK8;proprotein convertase subtilisin/kexin type 8;S1P;SEDKF;site-1 protease;SKI-1;subtilisin/kexin isozyme-1;Subtilisin/kexin-isozyme 1
- Weitere Details:
- The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice