GTX117180
LARGE antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX117180
- Zusätzliche Namen:
- LARGE xylosyl- and glucuronyltransferase 1 , LARGE , MDC1D , MDDGA6 , MDDGB6
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse, Rat
- Buffer:
- PBS, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human LARGE. The exact sequence is proprietary.
- Uniprot:
- O95461
- Synonyme:
- acetylglucosaminyltransferase-like 1A;acetylglucosaminyltransferase-like protein;Glycosyltransferase-like protein;glycosyltransferase-like protein LARGE1;LARGE;LARGE xylosyl- and glucuronyltransferase 1;MDC1D;MDDGA6;MDDGB6
- Weitere Details:
- This gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice