GTX116904
ITM2C antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX116904
- Zusätzliche Namen:
- integral membrane protein 2C , BRI3 , BRICD2C , E25 , E25C , ITM3
- Anwendung:
- Flow Cytometry, WB, IHC-P
- Konzentration:
- 0.7 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ITM2C. The exact sequence is proprietary.
- Uniprot:
- Q9NQX7
- Synonyme:
- BRI3;BRICD2C;BRICHOS domain containing 2C;cerebral protein 14;E25;E25C;integral membrane protein 2C;integral membrane protein 3;ITM3;transmembrane protein BRI3
- Weitere Details:
- Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
- Versandbedingungen:
- Blue Ice