GTX116696
GBA3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX116696
- Zusätzliche Namen:
- glucosylceramidase beta 3 (gene/pseudogene) , CBG , CBGL1 , GLUC , KLRP
- Anwendung:
- WB, IHC-P
- Konzentration:
- 0.55 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human GBA3. The exact sequence is proprietary.
- Uniprot:
- Q9H227
- Synonyme:
- CBG;CBGL1;cytosolic beta-glucosidase;cytosolic beta-glucosidase-like protein 1;cytosolic GCase;cytosolic glycosylceramidase;GLUC;glucosidase beta acid 3;glucosidase, beta, acid 3 (cytosolic);klotho-related protein;KLRP
- Weitere Details:
- GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM]
- Versandbedingungen:
- Blue Ice