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  2. Polyclonal

GTX116461

Langerin antibody [N2C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX116461
Zusätzliche Namen:
CD207 molecule , CLEC4K
Anwendung:
WB
Konzentration:
0.94 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the Extracellular domain of human Langerin. The exact sequence is proprietary.
Klon:
N2C3
Uniprot:
Q9UJ71
Synonyme:
C-type lectin domain family 4 member K;C-type lectin domain family 4, member K;CD207 antigen, langerin;CD207 molecule, langerin;CLEC4K;Langerhans cell specific c-type lectin;Langerin
Weitere Details:
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. [provided by RefSeq]
Versandbedingungen:
Blue Ice