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GTX116417
SIN3B antibody [N1N2-2], N-term
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX116417
- Zusätzliche Namen:
- SIN3 transcription regulator family member B
- Anwendung:
- WB, IF, ICC, IP
- Konzentration:
- 0.57 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human SIN3B. The exact sequence is proprietary.
- Klon:
- N1N2-2
- Uniprot:
- O75182
- Synonyme:
- histone deacetylase complex subunit Sin3b;paired amphipathic helix protein Sin3b;SIN3 homolog B, transcriptional regulator;SIN3 transcription regulator homolog B;transcriptional corepressor Sin3b
- Weitere Details:
- Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
- Versandbedingungen:
- Blue Ice