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  2. Polyclonal

GTX116308

STEAP3 antibody [N1C1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX116308
Zusätzliche Namen:
STEAP3 metalloreductase , AHMIO2 , STMP3 , TSAP6 , dudlin-2 , dudulin-2 , pHyde
Anwendung:
WB
Konzentration:
1.79 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
PBS, 20% Glycerol, 0.025% ProClin 300.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human STEAP3. The exact sequence is proprietary.
Klon:
N1C1
Uniprot:
Q658P3
Synonyme:
AHMIO2;dudlin-2;dudulin-2;metalloreductase STEAP3;pHyde;six-transmembrane epithelial antigen of prostate 3;STEAP family member 3, metalloreductase;STMP3;TSAP6;tumor suppressor pHyde;tumor suppressor-activated pathway protein 6
Weitere Details:
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Versandbedingungen:
Blue Ice