GTX11602
MMP3 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX11602
- Zusätzliche Namen:
- matrix metallopeptidase 3 , CHDS6 , MMP-3 , SL-1 , STMY , STMY1 , STR1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 15mM Sodium azide.
- Immunogen:
- synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-3 (stromelysin-1).
- Uniprot:
- P08254
- Synonyme:
- CHDS6;matrix metalloproteinase 3 (stromelysin 1, progelatinase);Matrix metalloproteinase-3;MMP-3;proteoglycanase;SL-1;STMY;STMY1;STR1;stromelysin-1;transin-1
- Weitere Details:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP3 is reported to be implicated in rheumatoid arthritis and some forms of cancer.
- Versandbedingungen:
- Blue Ice