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  2. Polyclonal

GTX115838

MTBP antibody [C2C3], C-term

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX115838
Zusätzliche Namen:
MDM2 binding protein , MDM2BP
Anwendung:
WB
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human MTBP. The exact sequence is proprietary.
Klon:
C2C3
Uniprot:
Q96DY7
Synonyme:
MDM2 (mouse double minute 2)-binding protein, 104kD;mdm2-binding protein;Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa;MDM2BP
Weitere Details:
Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.
Versandbedingungen:
Blue Ice