TRPC4AP antibody [N1N3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX115795
Zusätzliche Namen:: transient receptor potential cation channel subfamily C member 4 associated protein , C20orf188 , PPP1R158 , TRRP4AP , TRUSS
Anwendung:: WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the N-terminus region of human TRPC4AP. The exact sequence is proprietary.
Klon:: N1N3
Uniprot:: Q8TEL6
Synonyme:: C20orf188;PPP1R158;protein phosphatase 1, regulatory subunit 158;Protein TAP1;short transient receptor potential channel 4-associated protein;TNF-receptor ubiquitous scaffolding/signaling protein;TRP4-associated protein;trpc4-associated protein;TRRP4AP;TRUSS;tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein
Weitere Details:: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.

Versandbedingungen:: Blue Ice