GTX115435
DCTN2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX115435
- Zusätzliche Namen:
- dynactin subunit 2 , DCTN50 , DYNAMITIN , HEL-S-77 , RBP50
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human DCTN2. The exact sequence is proprietary.
- Uniprot:
- Q13561
- Synonyme:
- 50 kDa dynein-associated polypeptide;DCTN50;dynactin 2 (p50);dynactin complex 50 kDa subunit;dynactin subunit 2;DYNAMITIN;epididymis secretory protein Li 77;epididymis secretory sperm binding protein;HEL-S-77;p50 dynamitin;RBP50
- Weitere Details:
- This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice