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  2. Polyclonal

GTX115314

ARNT2 antibody [N2C1], Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX115314
Zusätzliche Namen:
aryl hydrocarbon receptor nuclear translocator 2 , WEDAS , bHLHe1
Anwendung:
WB
Konzentration:
0.47 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human, Mouse
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Mouse
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human ARNT2. The exact sequence is proprietary.
Klon:
N2C1
Uniprot:
Q9HBZ2
Synonyme:
ARNT protein 2;aryl hydrocarbon receptor nuclear translocator 2;bHLHe1;class E basic helix-loop-helix protein 1;WEDAS
Weitere Details:
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq]
Versandbedingungen:
Blue Ice