GTX11525
Endostatin antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX11525
- Zusätzliche Namen:
- collagen, type XVIII, alpha 1
- Anwendung:
- ELISA, WB, IHC-Fr
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Goat
- Reaktivitäten:
- Mouse
- Buffer:
- PBS, 5% Trehalose, no preservatives.
- Immunogen:
- purified recombinant mouse endostatin expressed in Sf21 cells.
- Uniprot:
- P39061
- Synonyme:
- alpha-1(XVIII) collagen;collagen alpha-1(XVIII) chain;endo;endostatin;procollagen, type XVIII, alpha 1
- Weitere Details:
- Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.
- Versandbedingungen:
- Blue Ice