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  2. Polyclonal

GTX114689

ABCD4 antibody [N1C1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX114689
Zusätzliche Namen:
ATP binding cassette subfamily D member 4 , ABC41 , EST352188 , MAHCJ , P70R , P79R , PMP69 , PXMP1L
Anwendung:
WB
Konzentration:
0.79 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human ABCD4. The exact sequence is proprietary.
Klon:
N1C1
Uniprot:
O14678
Synonyme:
69 kDa peroxisomal ABC-transporter;ABC41;ATP-binding cassette sub-family D member 4;ATP-binding cassette, sub-family D (ALD), member 4;EST352188;lysosomal cobalamin transporter ABCD4;MAHCJ;P70R;P79R;Peroxisomal membrane protein 1-like;peroxisomal membrane protein 69;PMP69;PMP70-related protein;PXMP1-L;PXMP1L
Weitere Details:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq]
Versandbedingungen:
Blue Ice