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  2. Polyclonal

GTX114679

PSMD4 antibody [N2C3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX114679
Zusätzliche Namen:
proteasome 26S subunit, non-ATPase 4 , AF , AF-1 , ASF , MCB1 , Rpn10 , S5A , pUB-R5
Anwendung:
WB, IF, ICC
Konzentration:
0.93 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human PSMD4. The exact sequence is proprietary.
Klon:
N2C3
Uniprot:
P55036
Synonyme:
26S proteasome non-ATPase regulatory subunit 4;26S proteasome regulatory subunit RPN10;26S proteasome regulatory subunit S5A;AF;AF-1;angiocidin;antisecretory factor 1;ASF;MCB1;multiubiquitin chain-binding protein;proteasome (prosome, macropain) 26S subunit, non-ATPase, 4;proteasome 26S subunit, non-ATPase 4;pUB-R5;Rpn10;S5A;S5a/antisecretory factor protein
Weitere Details:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq]
Versandbedingungen:
Blue Ice