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  2. Polyclonal

GTX114660

PPP3CC antibody [N1C1]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX114660
Zusätzliche Namen:
protein phosphatase 3 catalytic subunit gamma , CALNA3 , CNA3 , PP2Bgamma
Anwendung:
WB
Konzentration:
0.55 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human PPP3CC. The exact sequence is proprietary.
Klon:
N1C1
Uniprot:
P48454
Synonyme:
calcineurin, testis-specific catalytic subunit;Calmodulin-dependent calcineurin A subunit gamma isoform;CALNA3;CAM-PRP catalytic subunit;CNA3;PP2Bgamma;protein phosphatase 3, catalytic subunit, gamma isozyme;serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Weitere Details:
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).[supplied by OMIM]
Versandbedingungen:
Blue Ice