IPO5 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX114514
Zusätzliche Namen:: importin 5 , IMB3 , KPNB3 , Pse1 , RANBP5 , imp5
Anwendung:: IHC-P
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human, Mouse
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Mouse, Rat
Buffer:: PBS, 20% Glycerol, 0.01% Thimerosal.
Immunogen:: Recombinant protein encompassing a sequence within the C-terminus region of human IPO5. The exact sequence is proprietary.
Uniprot:: O00410
Synonyme:: IMB3;imp5;importin beta-3 subunit;importin subunit beta-3;importin-5;karyopherin (importin) beta 3;karyopherin beta-3;KPNB3;Pse1;RAN binding protein 5;Ran_GTP binding protein 5;ran-binding protein 5;RANBP5
Weitere Details:: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq]

Versandbedingungen:: Blue Ice