GTX114469
HIP2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX114469
- Zusätzliche Namen:
- ubiquitin conjugating enzyme E2 K , E2-25K , HIP2 , HYPG , LIG , UBC1
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human HIP2. The exact sequence is proprietary.
- Uniprot:
- P61086
- Synonyme:
- E2 ubiquitin-conjugating enzyme K;E2-25K;E2(25K);HIP-2;HIP2;huntingtin-interacting protein 2;HYPG;LIG;UBC1;ubiquitin carrier protein;ubiquitin conjugating enzyme E2K;ubiquitin-conjugating enzyme E2 K;ubiquitin-conjugating enzyme E2-25 KDA;ubiquitin-conjugating enzyme E2(25K);ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast);ubiquitin-protein ligase
- Weitere Details:
- The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
- Versandbedingungen:
- Blue Ice